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Viagra is an oral medication developed by Pfizer in the United States for the treatment of Erectile Dysfunction (ED). Its main ingredient is Sildenafil, with a dosage of 100mg per tablet. Viagra is also known as "Wan Ai Ke" and is highly effective in treating erectile dysfunction and premature ejaculation.
Origin of Viagra:
Sildenafil was developed by Pfizer in its research center in Sandwich, Kent, UK. It was initially intended as a PDE5 inhibitor for treating cardiovascular diseases and entered clinical trials. Researchers hoped that Sildenafil would release nitric oxide to relax cardiovascular smooth muscle, thereby dilating blood vessels and alleviating cardiovascular conditions. However, the first clinical trial at Morrison Hospital in Swansea showed that Sildenafil did not achieve the expected cardiovascular effects. Its performance as a cardiovascular drug was disappointing, and it failed to become a successful treatment.
In April 1991, the clinical study of Sildenafil was officially declared a failure. However, a side effect reported by trial participants caught the researchers' attention. They found that subjects were reluctant to return unused medication after receiving the drug. Upon investigation, it was discovered that the drug improved the subjects' sexual performance. With Pfizer management's approval, researchers began studying Sildenafil's effect on the smooth muscle of the corpus cavernosum. It received FDA approval on March 27, 1998, and quickly achieved commercial success. In 2008, Pfizer earned $1.934 billion from this product, making it a blockbuster that brought the company widespread recognition.
Mechanism of Action:
Viagra is an oral medication for treating male erectile dysfunction. It effectively promotes blood circulation in the male body, causing rapid expansion of the corpus cavernosum, leading to fast, firm, and thick erections. Over 85% of ED patients report satisfaction with Viagra's efficacy and improvement in sexual performance.
Target Users:
Adult males with reduced libido, weak erections, or impotence. After use, it quickly induces firm erections, enhances sexual quality, shortens the interval between sexual encounters, reduces fatigue, eliminates premature ejaculation, activates kidney function, and stimulates testicular cell secretion.
Side Effects:
The incidence of side effects from Viagra is approximately 2.5%, including mild headache (16%), facial flushing (11%), decreased appetite (7%), and temporary visual disturbances (3%). The probability of serious complications is less than 2%.
Common adverse reactions include dizziness, nasal congestion, indigestion, and temporary visual abnormalities such as difficulty distinguishing blue/green colors, increased light sensitivity, or blurred vision. These side effects are mostly due to related smooth muscle relaxation.
Dosage and Administration:
Avoid taking other sexual enhancement medications simultaneously with Viagra. Each tablet contains 100mg. First-time users may start with a lower dose: 1/4 or 1/2 tablet, then adjust based on individual response. If no effect is observed after several uses, discontinue use.
【Name】：Viagra (Wan Ai Ke)
【Ingredients】：Sildenafil 100mg per tablet
【Specifications】：4 tablets per box / 30 tablets per bottle
【Shelf Life】：Three years
【Manufacturer】：Pfizer Inc., USA
【Usage】：Take 1 tablet 1 hour before sexual activity. One tablet per dose.
【Precautions】：Avoid excessive dosage. Take once daily, one tablet at a time. Do not exceed the recommended dose. If a prolonged erection occurs, rinse the penis with cold water. 
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